Poco or POCO may refer to:

Postcolonialism

In musical notation, qualifier meaning "a little"

Poco (album), a 1970 album by the band Poco

Poco (band), an American country rock band formed in 1968

Plain Old CLR Object, term used by developers targeting the Common Language Runtime of the .NET Framework

POCO C++ Libraries, collection of open-source, C++, class libraries for network centric applications

"PoCo", a nickname for Port Coquitlam, British Columbia, Canada

POCO (company), a smartphone company

Poco, the playable character in Woody Poco, a Japanese video game released in 1986